Cibinetide · EPO-Derived 11-mer Tissue Protective Peptide
Erythropoietin-derived 11-mer peptide. Studied in nerve protection, neuropathic pain, and inflammatory pathway research without erythropoietic effects.
ARA-290 (Cibinetide) is an 11-amino acid peptide derived from the EPO helix B surface region. It activates the innate repair receptor (IRR) — a heterodimer of EPO receptor and CD131 — that mediates EPO's tissue-protective effects without erythropoietic activity. Research focuses on neuropathic pain, inflammation, and diabetic neuropathy models.
Store lyophilized at -20°C. Reconstitute in sterile saline. Stable 4 weeks at 2–8°C.