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RESEARCH

ARA-290

Cibinetide · EPO-Derived 11-mer Tissue Protective Peptide

Erythropoietin-derived 11-mer peptide. Studied in nerve protection, neuropathic pain, and inflammatory pathway research without erythropoietic effects.

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Research Data

What Is ARA-290?

ARA-290 (Cibinetide) is an 11-amino acid peptide derived from the EPO helix B surface region. It activates the innate repair receptor (IRR) — a heterodimer of EPO receptor and CD131 — that mediates EPO's tissue-protective effects without erythropoietic activity. Research focuses on neuropathic pain, inflammation, and diabetic neuropathy models.

Research Context

  • Innate repair receptor (IRR) activation without erythropoiesis
  • Neuropathic pain pathway research — small fiber neuropathy models
  • Anti-inflammatory effects via IRR-mediated macrophage modulation
  • Diabetic neuropathy pathway research — Phase 2 clinical data
  • Beta cell protection research in type 1 diabetes models

Storage & Reconstitution

Store lyophilized at -20°C. Reconstitute in sterile saline. Stable 4 weeks at 2–8°C.

All products sold for research purposes only. Not for human or animal consumption. Must be 18+ to purchase. By placing an order you confirm compliance with all applicable local laws and regulations.