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PE 22-28

DSIP Analog · BDNF Mimetic Heptapeptide

Short heptapeptide BDNF mimetic and DSIP analog. Studied in antidepressant, anxiolytic, and neuroprotective research models.

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Research Data

What Is PE 22-28?

PE 22-28 is a synthetic heptapeptide derived from the DSIP sequence, studied as a BDNF (Brain-Derived Neurotrophic Factor) loop 4 mimetic. Research has focused on antidepressant-like activity via TrkB receptor activation, anxiolytic effects, and stress-resilience models — without the limitations of full BDNF administration.

Research Context

  • TrkB receptor (BDNF receptor) activation research
  • Antidepressant and anxiolytic activity in animal models
  • Stress-resilience and HPA axis pathway studies
  • Comparison with Cerebrolysin in neurotrophic research
  • Blood-brain barrier penetrability studies

Storage & Reconstitution

Store lyophilized at -20°C. Reconstitute in bacteriostatic water. Use within 4 weeks at 2–8°C.

All products sold for research purposes only. Not for human or animal consumption. Must be 21 or older to purchase. By placing an order you confirm compliance with all applicable local laws and regulations.