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PE 22-28

Name: PE 22-28 Research Peptide
Brand: Purity Peptides
Price: 139 USD
Availability: InStock
Rating: 4.8 (89 reviews)

DSIP Analog · BDNF Mimetic Heptapeptide

Short heptapeptide BDNF mimetic and DSIP analog. Studied in antidepressant, anxiolytic, and neuroprotective research models.

✓ HPLC Verified ✓ 99%+ Purity ✓ COA Available ✓ Manufacturer Direct ✓ Direct Support

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Research Data

What Is PE 22-28?

PE 22-28 is a synthetic heptapeptide derived from the DSIP sequence, studied as a BDNF (Brain-Derived Neurotrophic Factor) loop 4 mimetic. Research has focused on antidepressant-like activity via TrkB receptor activation, anxiolytic effects, and stress-resilience models — without the limitations of full BDNF administration.

Research Context

TrkB receptor (BDNF receptor) activation research
Antidepressant and anxiolytic activity in animal models
Stress-resilience and HPA axis pathway studies
Comparison with Cerebrolysin in neurotrophic research
Blood-brain barrier penetrability studies

Storage & Reconstitution

Store lyophilized at -20°C. Reconstitute in bacteriostatic water. Use within 4 weeks at 2–8°C.

Peptide Calculator → Reconstitution Guide →

All products sold for research purposes only. Not for human or animal consumption. Must be 18+ to purchase. By placing an order you confirm compliance with all applicable local laws and regulations.