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RESEARCH

ACE-031

Activin Receptor Type IIB Decoy · Myostatin Pathway Inhibitor

Soluble decoy receptor targeting activin receptor type IIB (ActRIIB). Studied in muscle mass and bone density research models.

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Research Data

What Is ACE-031?

ACE-031 is a fusion protein combining the extracellular domain of activin receptor type IIB (ActRIIB) with an IgG1 Fc region. It acts as a decoy receptor, sequestering myostatin, activin, and GDF-11, thereby blocking their inhibitory effects on muscle growth. Research interest spans muscle-wasting diseases and athletic performance models.

Research Context

  • Myostatin pathway blockade and skeletal muscle mass research
  • GDF-11 and activin inhibition downstream effects
  • Bone mineral density pathway studies
  • Muscle-wasting disease models (DMD, ALS, cachexia)

Storage & Reconstitution

Store at 2–8°C (refrigerated, not frozen). Sensitive protein — avoid freeze-thaw cycles.

All products sold for research purposes only. Not for human or animal consumption. Must be 21 or older to purchase. By placing an order you confirm compliance with all applicable local laws and regulations.