IGF-1 LR3

Name: IGF-1 LR3 Research Peptide
Brand: Purity Peptides
Price: 105 USD
Availability: InStock
Rating: 4.6 (19 reviews)

Long-Arg3 IGF-1 · Extended-Life IGF Analog

★★★★★4.6 out of 5(19 reviews)

Long-R3 IGF-1 analog. Extended half-life for downstream GH signaling research.

✓ HPLC Verified ✓ 99%+ Purity ✓ COA Available ✓ Ships in 24hr ✓ US-Based ✓ Direct Support

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Research Data

What Is IGF-1 LR3?

IGF-1 LR3 (Long-Arg3 IGF-1) is a recombinant analog of insulin-like growth factor 1 with an arginine substitution at position 3 and an N-terminal extension, which reduces its binding affinity for IGF-binding proteins (IGFBPs) and extends its half-life from minutes (native IGF-1) to approximately 20–30 hours.

Research Context

IGF-1 receptor (IGF-1R) activation and downstream PI3K/AKT/mTOR signaling
Reduced IGFBP binding and extended tissue exposure vs native IGF-1
Skeletal muscle protein synthesis and satellite cell activation
Anti-apoptotic signaling and cellular survival pathways
Comparison with native IGF-1 for receptor pharmacology research

Storage & Reconstitution

Store at -20°C. Very sensitive to degradation — handle with care. Reconstituted in acetic acid (0.1M) or BAC water: use within 2–3 weeks refrigerated.

Peptide Calculator → Reconstitution Guide →