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Melanotan I

Afamelanotide · Linear Alpha-MSH Analog

MC1R-selective alpha-MSH analog. Studied in melanogenesis pathway models.

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Melanotan I research peptide vial
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$145
10-vial kit
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Research Data

What Is Melanotan I?

Melanotan I (afamelanotide) is a synthetic linear analog of alpha-melanocyte stimulating hormone (alpha-MSH). It activates MC1R receptors on melanocytes to stimulate eumelanin production, increasing skin pigmentation independent of UV radiation. It received EU approval (as Scenesse) for erythropoietic protoporphyria, providing clinical validation for MC1R-driven photoprotection.

Research Context

  • MC1R receptor activation and eumelanin synthesis in melanocytes
  • Photoprotection mechanism: melanin as UV radiation absorber
  • Comparison with Melanotan II for receptor selectivity (linear vs cyclic)
  • Erythropoietic protoporphyria research (EU-approved indication basis)
  • Melanogenesis pathway research in pigmentation biology

Storage & Reconstitution

Store lyophilized at -20°C. Reconstituted: 2–8°C, use within 4–6 weeks.

All products sold for research purposes only. Not for human or animal consumption. Must be 21 or older to purchase. By placing an order you confirm compliance with all applicable local laws and regulations.