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Melanotan II

Cyclic Alpha-MSH Analog · Non-Selective Melanocortin Agonist

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Non-selective melanocortin receptor agonist. Studied in melanocyte activation.

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Melanotan II research peptide vial
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$145
10-vial kit
+ $40 shipping · Free over $500 · Ships worldwide
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Research use only · Not for human consumption
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Research Data

What Is Melanotan II?

Melanotan II is a synthetic cyclic heptapeptide analog of alpha-MSH that non-selectively activates multiple melanocortin receptors (MC1R, MC3R, MC4R, MC5R). Its cyclic structure provides greater receptor binding potency vs the linear Melanotan I. MC4R activation produces additional CNS effects on appetite and sexual function, making it a broader melanocortin research tool.

Research Context

  • Non-selective melanocortin receptor agonism (MC1R/MC3R/MC4R/MC5R) and differential signaling
  • Eumelanin synthesis and UV-independent skin pigmentation research
  • MC4R-mediated CNS effects on appetite, libido, and arousal (precursor to PT-141)
  • Comparative receptor pharmacology vs selective MC1R agonists (Melanotan I)
  • Structure-activity relationships of cyclic vs linear alpha-MSH analogs

Storage & Reconstitution

Store lyophilized at -20°C. Reconstituted: 2–8°C, use within 4–6 weeks.

Peptide Calculator → Reconstitution Guide →
Related Compounds

Selective MC1R

Melanotan I

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Derived from MT2

PT-141

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Skin Peptide

GHK-Cu

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All products sold for research purposes only. Not for human or animal consumption. Must be 18+ to purchase. By placing an order you confirm compliance with all applicable local laws and regulations.