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PT-141

Bremelanotide · Melanocortin Receptor Agonist

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Melanocortin-4 receptor agonist. Studied in CNS-mediated pathway research.

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PT-141 research peptide vial
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$200
10-vial kit
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Research use only · Not for human consumption
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Research Data

What Is PT-141?

PT-141 (bremelanotide) is a cyclic heptapeptide melanocortin receptor agonist derived from Melanotan II. Unlike PDE5 inhibitors, it acts centrally through MC3R and MC4R receptors in the CNS to modulate sexual behavior pathways. It received FDA approval (as Vyleesi) for hypoactive sexual desire disorder in premenopausal women, providing clinical validation for its CNS-mediated mechanism.

Research Context

  • MC3R and MC4R central nervous system agonism and sexual behavior pathways
  • Comparison with PDE5 inhibitors (peripheral vs central mechanism)
  • Hypothalamic regulation of libido and arousal in animal and human models
  • Melanocortin receptor pharmacology and selectivity profiling
  • FDA approval basis: clinical data for HSDD in premenopausal women

Storage & Reconstitution

Store lyophilized at -20°C. Reconstituted: 2–8°C, use within 4–6 weeks. Kit only.

Peptide Calculator → Reconstitution Guide →
Related Compounds

Melanocortin Agonist

Melanotan II

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GnRH Stimulator

KissPeptin

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Bonding Peptide

Oxytocin

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All products sold for research purposes only. Not for human or animal consumption. Must be 18+ to purchase. By placing an order you confirm compliance with all applicable local laws and regulations.