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Retatrutide

LY3437943 · GLP-1/GIP/Glucagon Triple Agonist

Triple-agonist GLP-1/GIP/glucagon receptor agonist. Most studied compound in metabolic research.

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Retatrutide research peptide vial
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$150
10-vial kit
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Research Data

What Is Retatrutide?

Retatrutide (LY3437943) is a GIP/GLP-1/glucagon triple receptor co-agonist in Phase 3 clinical investigation. Phase 2 NEJM data (2023) demonstrated up to 24.2% mean body weight reduction at 48 weeks, the highest reported for any incretin-class compound.

Research Context

  • Triple receptor agonism (GLP-1/GIP/glucagon) as a metabolic research model
  • Adiposity reduction and body composition in clinical trial populations
  • Hepatic lipid metabolism and NAFLD pathway modulation
  • Comparative receptor pharmacology vs dual agonists and monoagonists
  • Glucagon receptor contribution to energy expenditure

Storage & Reconstitution

Store lyophilized at -20°C for 12–24 months. Reconstituted in BAC water: refrigerate at 2–8°C, use within 4–6 weeks.

All products sold for research purposes only. Not for human or animal consumption. Must be 21 or older to purchase. By placing an order you confirm compliance with all applicable local laws and regulations.