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RESEARCH
RESOURCES

The complete educational hub for peptide research. Guides, calculators, stacking references, and curated academic literature for every compound we carry.

Research Use Only Free Tools Beginner to Advanced
Research purposes only. All content in this library is for educational and in-vitro research use only. Compounds referenced on this site are sold strictly for laboratory research. Not for human or animal consumption. Purity Peptides does not provide medical advice, diagnosis, or treatment guidance.
/ Tools & Guides

START HERE

Four essential resources for any researcher. Start with Peptide 101 if you're new, or jump straight to the calculator or stacking guide.

Beginner Guide
01
Peptide 101
What is a research peptide? How lyophilization works, why purity matters, and what COAs actually tell you. Start here if you're new.
Read Guide →
 Preparation Guide
02
Reconstitution Guide
Step-by-step: how to reconstitute any lyophilized peptide with bacteriostatic water. Includes supplies list, storage rules, and FAQ.
Read Guide →
 Interactive Tool
03
Dosing Calculator
Enter vial size and BAC water volume to get concentration, per-unit dose, and a full syringe reference table. Works for any peptide.
Open Calculator →
 Stacking Reference
04
Peptide Stacking Guide
Popular research stacks: GH optimization, body composition, recovery, and anti-aging. Rationale, compound roles, and timing references.
View Stacks →
/ Compound Reference

PRODUCT RESEARCH PAGES

Detailed research pages for every compound we carry. Mechanism, clinical data, variants, reconstitution notes, and COA links.

Metabolic Research
GLP-1 / GIP / Glucagon
Retatrutide (GLP-3)
Triple agonist. Mechanism, Phase 2 trial data, variants, reconstitution, and COA.
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 GLP-1 / GIP
Tirzepatide
Dual GIP/GLP-1 agonist. SURMOUNT trial data, receptor pharmacology, and research context.
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 GLP-1
Semaglutide
GLP-1 receptor agonist. STEP-1 trial context, metabolic research, peptide structure.
View Page →
Tissue Research
Tissue / Gut
BPC-157
Gastric pentadecapeptide. Tissue repair, angiogenesis, and gut barrier research context.
View Page →
 Actin / Angiogenesis
TB-500 (Thymosin Beta-4)
Actin-sequestering peptide. Tissue repair, inflammation modulation, and neovascularization research.
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GH Secretagogues
Pituitary / IGF-1
HGH (Somatropin)
Recombinant human growth hormone. Pituitary axis, IGF-1 axis, and research applications.
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 GHRP / GHRH
Ipamorelin / CJC-1295
GHRP + GHRH combination stack. GH pulse amplitude and frequency research.
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Skin & Anti-Aging
Dermal / Collagen
GHK-Cu
Copper tripeptide. Collagen synthesis, wound healing, and anti-aging research context.
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 Mitochondrial
NAD+
Nicotinamide adenine dinucleotide. Mitochondrial function, sirtuin activation, and aging research.
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Melanocortin & Endocrine Research
MC-R Agonist
Melanotan II
Melanocortin receptor agonist. Melanogenesis, UV protection research, and MC-R pharmacology.
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 CNS / Endocrine
PT-141 (Bremelanotide)
Melanocortin agonist. CNS-mediated research applications and receptor pharmacology.
View Page →
Neuropeptide Research
ACTH-Derived / BDNF
Semax
ACTH-derived nootropic peptide. BDNF upregulation and neuroprotection research context.
View Page →
/ Academic Literature

CURATED STUDIES

Peer-reviewed references curated for the compounds we carry. Links open directly on PubMed or the journal of record.

GLP-1 / Metabolic Research
Retatrutide Phase 2 Trial — Triple Agonist for Obesity
Jastreboff et al. · NEJM 2023 · GLP-1/GIP/Glucagon
Phase 2 dose-escalation trial of retatrutide (LY3437943) in adults with obesity. Mean body weight reduction of up to 24.2% at 48 weeks.
PubMed ↗
SURMOUNT-1 — Tirzepatide for Obesity (Phase 3)
Jastreboff et al. · NEJM 2022 · PMID 35658024
72-week randomized trial. Tirzepatide 15mg produced 20.9% mean body weight reduction vs. 3.1% for placebo. Established benchmark for GIP/GLP-1 dual agonism.
PubMed ↗
STEP-1 — Semaglutide 2.4mg for Weight Management
Wilding et al. · NEJM 2021 · PMID 33567185
68-week trial. Semaglutide produced 14.9% mean body weight reduction. First phase 3 GLP-1 data to demonstrate double-digit weight loss vs. placebo.
PubMed ↗
AOD-9604 — Anti-Obesity Effects of GH Fragment
Heffernan et al. · Am J Physiol Endocrinol Metab 2001
AOD-9604 (hGH fragment 176-191) stimulates lipolysis and inhibits lipogenesis in adipocytes without affecting insulin sensitivity or IGF-1 levels.
PubMed ↗
Tissue Research
BPC-157 — Stable Gastric Pentadecapeptide: Review
Sikiric et al. · Curr Pharm Des 2018 · PMID 30027844
Comprehensive review of BPC-157's proposed mechanisms: angiogenesis, growth factor modulation (VEGF, EGF), and gut-brain axis interactions across animal models.
PubMed ↗
Thymosin Beta-4 (TB-500) in Tissue Repair and Angiogenesis
Goldstein & Kleinman · Ann NY Acad Sci 2015 · PMID 25773628
Review of thymosin beta-4's role in wound healing, actin polymerization regulation, and promotion of neovascularization. Active area of wound care research.
PubMed ↗
KPV Tripeptide — Anti-Inflammatory Mechanisms
Dalmasso et al. · J Crohns Colitis 2008
Alpha-MSH-derived tripeptide KPV demonstrates anti-inflammatory properties in intestinal epithelial cells via NF-kB pathway inhibition in preclinical models.
PubMed ↗
Dermal Research
GHK-Cu — Human Skin Remodeling via Copper Peptide
Pickart & Margolina · Biomolecules 2018 · PMID 30022165
GHK-Cu stimulates collagen and glycosaminoglycan synthesis, activates antioxidant enzymes, and modulates over 4,000 human genes including those controlling skin repair.
PubMed ↗
Epithalon — Telomere Elongation and Aging
Khavinson et al. · Bull Exp Biol Med 2003 · PMID 14631430
Tetrapeptide Epithalon (Epitalon) demonstrated telomerase activation in human somatic cells in vitro, increasing telomere length and extending cellular lifespan in preclinical models.
PubMed ↗
Melanotan II — Melanocortin Receptor Pharmacology
Wikberg · Pharmacol Res 1999 · PMID 10588310
Review of melanocortin receptor subtypes (MC1R-MC5R), ligand selectivity, and research applications. Foundational pharmacology reference for Melanotan analogs.
PubMed ↗
GH Secretagogues
Ipamorelin — Selective GH Secretagogue Without Cortisol Effect
Raun et al. · Eur J Endocrinol 1998 · PMID 9820010
Ipamorelin selectively stimulates GH release with minimal effect on prolactin, ACTH, or cortisol, distinguishing it from earlier GHRPs. Foundational selectivity study.
PubMed ↗
CJC-1295 — Sustained GH and IGF-1 Elevation
Teichman et al. · J Clin Endocrinol Metab 2006 · PMID 16352683
CJC-1295 (with DAC) produced dose-dependent increases in GH and IGF-1 levels lasting up to 6 days in healthy adults. First CJC-1295 human pharmacokinetic data.
PubMed ↗
Tesamorelin — Visceral Adiposity Reduction in Clinical Trial
Falutz et al. · NEJM 2010 · PMID 20427812
Randomized trial of tesamorelin (GHRH analog) demonstrating significant reduction in visceral adipose tissue. FDA-approved application as reference for GHRH analog research.
PubMed ↗
Mitochondrial & Neuropeptide Research
MOTS-C — Mitochondrial-Derived Peptide Regulating Metabolism
Lee et al. · Cell Metab 2015 · PMID 25738459
Discovery paper for MOTS-C. Mitochondrial-encoded peptide that regulates nuclear gene expression, enhances insulin sensitivity, and promotes metabolic homeostasis in mice.
PubMed ↗
NAD+ Metabolism and Its Role in Aging
Yoshino et al. · Cell Metab 2018 · PMID 30243858
Oral NMN supplementation restored NAD+ levels and improved muscle insulin sensitivity in postmenopausal women with prediabetes. Key NAD+ metabolism human trial.
PubMed ↗
Semax — BDNF Upregulation and Neuroprotection
Dolotov et al. · J Neurochem 2006 · PMID 16643424
ACTH-derived heptapeptide Semax increases BDNF and NGF expression in rat brain. Mechanism study for Semax's observed neuroprotective and nootropic effects in preclinical models.
PubMed ↗
Selank — Anxiolytic and Nootropic Effects
Zozulya et al. · CNS Drug Rev 2001 · PMID 11455789
Tuftsin analog Selank demonstrated anxiolytic activity and memory enhancement in animal models. Review covers receptor interaction and GABAergic modulation mechanisms.
PubMed ↗
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